提供: Vaccipedia | Resources for Vaccines, Tropical medicine and Travel medicine
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General issues of Vaccine
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General issues of Tropical med.
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General issues of Travel med.
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Trematode (fluke, distoma)
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pathogen
- Neisseria meningitidis
- gram negative diplococci
- carriage in nasopharynx
- 12 identified capsular serogroups
- common pathogenic serogroup A, B, C, W, X, Y
- seasonal epidemics by group A, C
- sporadic cases by e.g. group B
epidemiology
- highest < 2 y/o and adolescent
why natural carriage differs between countries
clinical picture
- fever
- distinctive petechiae anywhere in whole body
- no fading by pressure with glass tumbler - "tumbler test"
- resulting in purple bruising of skin
- photophobia
- headache, neck stiffness, vomiting
- irritability and/or confusion