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General issues of Vaccine
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General issues of Tropical med.
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General issues of Travel med.
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Trematode (fluke, distoma)
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risk of TB even at high CD4 count
- CD4 cell depletion
- TB-specific T cell↓
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TB exacerbates HIV infection
- increase HIV replication in TB granuloma
ART significantly reduces TB incidence
drug interaction
- RFP induces CYP
- RFP accelerates metabolism of PI, some NNRTI and INI
IRIS
- major criterion
- active TB < 3 months of initiation of ART
- minor criteria