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General issues of Vaccine
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General issues of Tropical med.
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General issues of Travel med.
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Trematode (fluke, distoma)
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morphology
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Anopheles |
Culex |
Aedes
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resting
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rest at an angle on wall surface
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rest with body parallel to surface
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adult color
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black and white
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larvae
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no siphon
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long siphon
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short siphon
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egg
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laid singly, floating
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collected in egg raft, floating
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laid singly, deposited on damp surface
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- Mansonia
- Coquillettidia
- larvae siphon piercing into a root of water plants to breathe
- Haemagogous
- Sabethes
- only in Central and South America
- metallically colored body
- dry tolerant eggs
mosquito-borne disease
arbovirus
- arthropod-borne virus
- family Togaviridae, Flaviviridae, Bunyaviridae, Reoviridae, Rhabdoviridae
Aedes-borne disease
- 932 species in the world
- 40 species transmit pathogens
- dengue
- yellow fever
- chikungunya
- zika
Aedes aegypti |
Aedes albopictus
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yellow fever mosquito |
asian tiger mosquito
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crescend-shaped white scale lines
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straight white line
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prefer small water containers to breed
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feed blood in daytime
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laid eggs on damp surface eggs resistant to desiccation, eggs alive 3-6 months under dry condition
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only in tropics and subtropics |
worldwide including temperate region
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prefers urban area |
prefers transitional to rural area
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prefers inside house |
prefers outside
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originated from Africa |
originated from Asia
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produce diapause eggs
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- diapause eggs of A. albopictus
- eggs laid during winter are resistant to dry as well as cold environment
- premature larvae developed and stop developing during winter
- female albopictus produce diapause when sunlight duration gets shorter and temperature lower
- individuals living in areas northern to tropic of Cancer produce diapause eggs
- ones living in tropics never produce diapause eggs
bridging vector
- vectors that transmit pathogen from infected wild animals and subsequently transmit the pathogen to humans
- not always prefer human to feed, nor live close to human
- yellow fever vectors in savannah cycle between sylvatic cycle and urban cycle are bridging vector
- spillout of pathogen from animal
Culex-borne disease
- Culex tritaeniorhyncus
- JEV - Cx. tritaeniorhyncus is bridging vector
- Cx. pipiens complex
- 4 subspecies
- West Nile virus - Cx. pipiens complex are bridging vectors
- hybridazation of Culex may have brought introduction of WNV into North America
- Lymphatic filariasis
- Wuchereria bancrofti
- Brugia malayi
- Brugia timori
- various Culex species are attributable to transmission of microfilaria
Anopheles
Morphology
- 肢にwhite spotsが多数ある
- Anophelesのlarvaeは水面近くで横向きに浮く
- ova is boat-shaped, laid and floated singly on water surface
Blood-sucking activity
Vector function
- Only 30-40 species transmit human malaria
anopheles in Africa
- An. gambiae complex
- 8 species in all
- morphologically similar
- prevalent broadly in sub-Saharan Africa
- An. gambiae sensu stricto (s.s.)
- An. arabiensis (except around DRC)
- prevalent only eastern Africa
- prevalent only western Africa
- An. funestus group
- 9 species in all
- morphologically distinguishable
- most important
tendency
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An. arabiensis |
An. gambiae |
An. funestus
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Blood meal preference
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more of livestock
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more of human
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Adult resting site
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more outdoor
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more indoor
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Breeding site
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small and open
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large and vegi
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