General issues of Helminths
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Nematode (roundworm) | |||||||||||||||||
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Trematode (fluke, distoma) | |||||||
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Cestode (tapeworm) | ||||||
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Medical Zoology | ||||||||
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Medicine for helminths
Nematode | Trematode | Cestode | |
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Diethylcarbamazine (DEC)
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Ivermectin
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Albendazole | |||
Praziquantel | |||
Triclabendazole | |||
Doxycycline | |||
Surgical/Mechanical removal | |||
Spontaneous resolution/ No effective treatment |
Treatment options of Lymphatic filariasis, Onchocerciasis and Loiasis
Lymphatic filariasis | Onchocerciasis | Loiasis | |
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Diethylcarbamazine (DEC) | 1st line | NEVER possibly Mazzotti |
<8,000 MF/mL |
Ivermectin | 1st line but Mazzotti 10% |
NEVER possibly encephalopathy | |
Albendazole | >8,000 MF/mL |
Lymphatic filariasis | LF & Oncho | Onchocerciasis | Oncho & Loiasis | Loiasis | |
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Diethylcarbamazine (DEC) | 1st line | NEVER | NEVER | NEVER | <8,000 MF/mL |
Ivermectin | Ivermectin + Albendazole may be safe |
1st line but Mazzotti 10% |
NEVER | NEVER | |
Albendazole | may be an option | >8,000 MF/mL | |||
Other option | Cytapheresis of oncho MF before DEC |
※MF = microfilariae